登记号
CTR20140137
相关登记号
CTR20130843;
曾用名
药物类型
化学药物
临床申请受理号
企业选择不公示
适应症
发生急性冠脉综合征的2型糖尿病患者
试验通俗题目
Aleglitazar降低近期发生ACS的T2D患者心血管风险的可能性
试验专业题目
一项心血管结局的临床研究－旨在评价Aleglitazar降低近期发生急性冠脉综合征的2型糖尿病患者心血管风险的可能性
试验方案编号
BC22140 第E版
方案最近版本号
版本日期
方案是否为联合用药
企业选择不公示
申请人信息
申请人名称
联系人姓名
吴瑜铭
联系人座机
+86 20 2908 2366
联系人手机号
联系人Email
saffi.wu@roche.com
联系人邮政地址
广东省广州市越秀区中山三路33号中华国际中心B座22楼罗氏（中国）投资有限公司临床试验执行部
联系人邮编
510055
临床试验信息
试验分类
安全性和有效性
试验分期
III期
试验目的
明确Aleglitazar是否能降低近期发生ACS事件的T2D患者的心血管死亡率和发病率（非致死性心肌梗死和非致死性卒中）
随机化
随机化
盲法
双盲
试验范围
国际多中心试验
设计类型
平行分组
年龄
19岁(最小年龄)至
NA岁(最大年龄)
性别
男+女
健康受试者
无
入选标准
- 年龄大于18岁的男性或女性
- 已知或诊断T2D或新诊断T2D（应在随机之前根据美国糖尿病学会诊断标准进行确诊）
- 患者因ACS事件住院治疗，且在出院日和ACS指示性事件（住院当天）之后的8周之间完成随机。如在导入期再次发生ACS事件、操作相关的心肌梗死或冠脉搭桥手术，应在该事件发生后经研究者判断患者病情稳定后随机，但是不能晚于这次新发事件后的8周。对于这些患者，从指示性事件发生至随机最长间隔时间为12周
- 能够并愿意出具书面知情同意书，并遵守本研究的要求
排除标准
- 合并使用噻唑烷二酮类和/或贝特类药物
- 既往对噻唑烷二酮类和/或贝特类药物不耐受
- 甘油三酯（空腹检测值）大于400 mg/dL（大于4.5 mmol/L）
- 有临床症状明显的肝脏疾病，如黄疸、胆汁淤积、肝脏损害、活动性肝炎或无症状ALT大于3x ULN
- 贫血，定义为血红蛋白小于10g/dL（小于100 g/L，6.21 mmol/L）或红细胞压积小于30%
- eGFRMDRD 小于45 ml/min/1.73m2
- 症状性充血性心力衰竭，NYHA分级为II-IV级的患者。法国和德国：症状性充血性心力衰竭，NYHA分级为I-IV级
- 发生指示性事件前12个月内曾因心力衰竭为主要诊断接受入院治疗
- 患者出现了经研究者判断为临床严重的外周水肿
- 筛查前三个月内接受过两周以上的系统性全身激素治疗
- 研究者判定有任何干扰研究实施的严重医学状况
- 合并严重疾病，使患者预期寿命短于研究持续时间（例如全身急性感染、癌症或其它严重疾病）。随机前曾发生且已得到治疗的基底细胞癌患者可纳入研究
- 不愿意或无法遵守研究要求（包括因吸毒或酗酒导致其不可靠的受试者）
- 妊娠试验阳性、哺乳期妇女以及没有采取有效避孕措施的有生育可能的女性
- 在筛查前的一个月内参加过任何关于研究药物或器械的临床试验
试验分组
试验药
| 名称 | 用法 |
|---|---|
|
中文通用名:Aliglitazar
|
用法用量:片剂，150μg每片，每日1次口服150μg的Aleglitazar或匹配的安慰剂，整个研究的服药时间最好相同
|
对照药
| 名称 | 用法 |
|---|---|
|
中文通用名:和Aleglitazar相匹配的安慰剂片剂
|
用法用量:片剂，150μg每片，每日1次口服150μg的Aleglitazar或匹配的安慰剂，整个研究的服药时间最好相同
|
终点指标
主要终点指标
| 指标 | 评价时间 | 终点指标选择 |
|---|---|---|
| 首次发生临床事件委员会判定的构成主要复合终点的任何一个组成事件的时间。构成主要复合终点的组成事件包括心血管死亡、非致死性心肌梗死和非致死性卒中。 | 两组至少发生950件CEC判定的主要事件，预期在最后一名患者随机后2年半 | 有效性指标 |
次要终点指标
| 指标 | 评价时间 | 终点指标选择 |
|---|---|---|
| 首次出现以下终点事件时的时间：心血管死亡、非致死性MI、因生物标志物阴性ACS而住院治疗3和非致死性卒中；由以下事件所构成的复合终点：所有死亡、非致死MI和非致死性卒中；以上复合终点中的单个组成事件：非预期计划的（不包括随机前计划好的）冠脉血运重建。 | 两组至少发生950件CEC判定的主要事件，预期在最后一名患者随机后2年半 | 有效性指标 |
| Aleglitazar对血糖控制、脂蛋白谱、血压和心血管风险的生物标志物的作用 | 两组至少发生950件CEC判定的主要事件，预期在最后一名患者随机后2年半 | 有效性指标 |
| Aleglitazar的耐受性和长期安全性（同时特别关注PPAR已知的不良事件，例如体液潴留、心力衰竭、骨折、肾功能改变、肌肉骨骼不良事件和肝酶升高） | 两组至少发生950件CEC判定的主要事件，预期在最后一名患者随机后2年半 | 有效性指标+安全性指标 |
| 生命体征、体格检查、临床实验室检查、体重。如有数据，还将对ECG和左室射血分数进行审评。 | 两组至少发生950件CEC判定的主要事件，预期在最后一名患者随机后2年半 | 安全性指标 |
数据安全监察委员会（DMC）
无
为受试者购买试验伤害保险
无
研究者信息
| 姓名 | 学位 | 职称 | 电话 | 邮政地址 | 邮编 | 单位名称 | |
|---|---|---|---|---|---|---|---|
| 胡大一 | 教授 | +86 10 88324876 | dayi.hu@medmail.com.cn | 北京市西城区西直门南大街11号 | 100044 | 北京大学人民医院 |
各参加机构信息
| 机构名称 | （主要）研究者 | 国家 | 地区 | 城市 |
|---|---|---|---|---|
| 北京大学人民医院 | 胡大一 | 中国 | 北京 | 北京 |
| 浙江医院 | 严静 | 中国 | 浙江 | 杭州 |
| 青岛市立医院 | 张放 | 中国 | 山东 | 青岛 |
| 山东大学齐鲁医院 | 张运 | 中国 | 山东 | 济南 |
| 四川大学华西医院 | 胡宏德 | 中国 | 四川 | 成都 |
| 东南大学附属中大医院 | 马根山 | 中国 | 江苏 | 南京 |
| 同济大学附属同济医院 | 罗明 | 中国 | 上海 | 上海 |
| 中国医学科学院北京协和医院 | 严晓伟 | 中国 | 北京 | 北京 |
| 中国医科大学附属盛京医院 | 李晓东 | 中国 | 辽宁 | 沈阳 |
| 浙江大学医学院附属邵逸夫医院 | 傅国胜 | 中国 | 浙江 | 杭州 |
| 北京朝阳医院 | 杨新春 | 中国 | 北京 | 北京 |
| 包头市中心医院 | 赵瑞平 | 中国 | 内蒙古自治区 | 包头 |
| 辽宁省人民医院 | 李占全 | 中国 | 辽宁 | 沈阳 |
| 大庆油田总医院 | 黎辉 | 中国 | 黑龙江 | 大庆 |
| 西安交通大学医学院第一附属医院 | 袁祖贻 | 中国 | 陕西 | 西安 |
| 中国人民解放军总医院 | 陈韵岱 | 中国 | 北京 | 北京 |
| 北京安贞医院 | 马长生 | 中国 | 北京 | 北京 |
| 广西医科大学第一附属医院 | 李浪 | 中国 | 广西壮族自治区 | 南宁 |
| 中国人民解放军第二炮兵总医院 | 胡桃红 | 中国 | 北京 | 北京 |
| 中日友好医院 | 柯元南 | 中国 | 北京 | 北京 |
| 上海市徐汇区中心医院 | 顾水明 | 中国 | 上海 | 上海 |
| 复旦大学附属华山医院 | 施海明 | 中国 | 上海 | 上海 |
| 浙江大学医学院附属第一医院 | 陈君柱 | 中国 | 浙江 | 杭州 |
| 广东省人民医院 | 陈纪言 | 中国 | 广东 | 广州 |
| 北京世纪坛医院 | 彭建军 | 中国 | 北京 | 北京 |
| 上海市第六人民医院 | 魏盟 | 中国 | 上海 | 上海 |
| 中国人民解放军第三零六医院 | 王晓非 | 中国 | 北京 | 北京 |
| 首都医科大学附属北京友谊医院 | 李虹伟 | 中国 | 北京 | 北京 |
| 上海市胸科医院 | 方唯一 | 中国 | 上海 | 上海 |
| 上海交通大学医学院附属第九人民医院 | 吴士尧 | 中国 | 上海 | 上海 |
| 湖南省人民医院 | 郭莹 | 中国 | 湖南 | 长沙 |
| 中山大学附属第一医院 | 马虹 | 中国 | 广东 | 广州 |
| 上海市第十人民医院 | 李伟明 | 中国 | 上海 | 上海 |
| 大连医科大学附属第一医院 | 刘俊 | 中国 | 辽宁 | 大连 |
| 中南大学湘雅第三医院 | 杨侃 | 中国 | 湖南 | 长沙 |
| 武汉大学中南医院 | 干学东 | 中国 | 湖北 | 武汉 |
| 白求恩国际和平医院 | 王东梅 | 中国 | 河北 | 石家庄 |
| 上海交通大学医学院附属仁济医院 | 何奔 | 中国 | 上海 | 上海 |
| 中国人民解放军沈阳军区总医院 | 韩雅玲 | 中国 | 辽宁 | 沈阳 |
| 254医院 | 李慧敏 | 中国 | 天津 | 天津 |
| 北京军区总医院 | 吕肖锋 | 中国 | 北京 | 北京 |
| 中南大学湘雅二医院 | 赵水平 | 中国 | 湖南 | 长沙 |
| CEDIC - Centro de Investigacion Clinica | Elizabeth Gelersztein | ARGENTINA | Buenos Aires | Buenos Aires |
| Centro Mod. de. Cardiologia | Andrea Piredda | ARGENTINA | Tucuman | Tucuman |
| Clinica Chutro SRL | Horacio Jure | ARGENTINA | Cordoba | Cordoba |
| Clinica Constituyentes | Daniel Nul | ARGENTINA | Moron | Moron |
| Clinica Coronel Suarez | Alberto CACCAVO | ARGENTINA | Coronel Suarez | Coronel Suarez |
| Clinica de Nefrología, Urología y Enfermedades Cardiovasculares Servicio de Nefrología | Cristian Botta | ARGENTINA | Santa Fe | Santa Fe |
| CONSULTORIOS ASOCIADOS DE ENDOCRINOLOGIA | LAURA MAFFEI | ARGENTINA | Buenos Aires | Buenos Aires |
| Consultorios De La Clinica Centro Medico Alcorta | Javier Marino | ARGENTINA | Haedo | Haedo |
| Hospital Britanico | Horacio Avaca | ARGENTINA | Ciudad Autonoma Bs As | Ciudad Autonoma Bs As |
| Hospital Cosme Argerich | Alfredo Piombo | ARGENTINA | Buenos Aires | Buenos Aires |
| Hospital Italiano De Buenos Aires; Unidad Coronaria. | Jose Navarro | ARGENTINA | Buenos Aires | Buenos Aires |
| Instituto Cardiovascular Buenos Aires | Diego Conde | ARGENTINA | Buenos Aires | Buenos Aires |
| Instituto de Cardiologia de Corrientes | Juan Pablo Cimbaro Canella | ARGENTINA | Corrientes | Corrientes |
| Instituto de Cardiologia Dr. Luis Gonzalez Sabathié | Néstor Vita | ARGENTINA | Rosario | Rosario |
| Instituto De Investigaciones Clinicas Zarate | Marisa Liliana Vico | ARGENTINA | Zarate | Zarate |
| Instituto Medico CENESA | Sebastian Saravia Toledo | ARGENTINA | Salta | Salta |
| Investogaciones Clinicas Tucuman | Eduardo Hasbani | ARGENTINA | Tucuman | Tucuman |
| IPAC Clinica Privada Caraffa | Hugo Ramos | ARGENTINA | Cordoba | Cordoba |
| Sanatorio Britanico S.A. | Daniel Piskorz | ARGENTINA | Rosario | Rosario |
| Sanatorio Guemes | Luis Sztejfman | ARGENTINA | Capital Federal | Capital Federal |
| Sanatorio San Francisco | Pablo Guzman | ARGENTINA | Ballarat | Ballarat |
| Bankstown Hospital | Jens Kilian | ARGENTINA | BANKSTOWN | BANKSTOWN |
| Canberra Hospital | LEON ARDARNOLDA | AUSTRALIA | WODEN | WODEN |
| Concord Repatriation General Hospital; Cardiology Department | David Brieger | AUSTRALIA | CONCORD | CONCORD |
| Core Research Group; Cardiology | David Colquhoun | AUSTRALIA | Milton | Milton |
| Geelong Hospital; Geelong Cardiology Practice | John Amerena | AUSTRALIA | Geelong | Geelong |
| John Hunter Hospital | Nicholas Collins | AUSTRALIA | Hunter Region | Hunter Region |
| Liverpool Hospital | Sidney Lo | AUSTRALIA | Liverpool BC | Liverpool BC |
| Lyell McEwin Hopspital; Dept of Cardiology | Margaret Arstall | AUSTRALIA | Elizabeth Vale | Elizabeth Vale |
| Princess Alexandra Hospital | Paul Garrahy | AUSTRALIA | Woolloongabba | Woolloongabba |
| Royal Adelaide Hospital; Cardiovascular Clinical Trials Unit | Matthew Worthley | AUSTRALIA | Adelaide | Adelaide |
| Royal North Shore Hospital | Gregory Nelson | AUSTRALIA | Sydney | Sydney |
| St. George Public Hospital | Ananth Prasan | AUSTRALIA | Sydney | Sydney |
| ST VINCENT'S HOSPITAL | Stephanie Wilson | AUSTRALIA | DARLINGHURST | DARLINGHURST |
| TOWNSVILLE GENERAL HOSPITAL | Raibhan Yadav | AUSTRALIA | DOUGLAS | DOUGLAS |
| Wollongong Hospital; Cardiac Research | Tuan Hoai Nguyen Dang | AUSTRALIA | Wollongong | Wollongong |
| Santa Casa de Misericordia de Belo Horizonte | Gilmar Reis | BRAZIL | Belo Horizonte | Belo Horizonte |
| Cedh - Centro De Estudos Em Diabetes E Hipertensao | Adriana Forti | BRAZIL | Fortaleza | Fortaleza |
| Centro de Pesquisa Clinica do Brasil | Joao Borges | BRAZIL | BRASILIA | BRASILIA |
| Centro de Pesquisas Clinicas; CPCLIN | Celia Regina Sampaio | BRAZIL | Sao Paulo | Sao Paulo |
| Centro de Pesquisas em Diabetes - CPD | Jorge Luiz Gross | BRAZIL | Porto Alegre | Porto Alegre |
| Centro De Pesquisas Em Diabetes E Doencas Endocrino-Metabolicas | Miguel Hissa | BRAZIL | Forlateza | Forlateza |
| Clinica Bastos | Fabio Santos | BRAZIL | Campinas | Campinas |
| ENCORE Cardiologia e Radiologia Intervencionista | Jose Antonio Jatene | BRAZIL | Goiania | Goiania |
| Fundacao Bahiana de Cardiologia - FBC | Alvaro Alves Junior | BRAZIL | Salvador | Salvador |
| Hospital Angelina Caron | Dalton Precoma | BRAZIL | Campina Grande do Sul | Campina Grande do Sul |
| Hospital Cardiologico Costantini | Costantino Roberto Frack | BRAZIL | Curitiba | Curitiba |
| Hospital of cynical FMUSP foundation Zerbini / HC FMUSP Institute of sao Paulo heart incor | Raul Santos Filho | BRAZIL | Sao Paulo | Sao Paulo |
| Hospital das Cínicas FMUSP Fundacao Zerbini / HC da FMUSP Instituto do Coracao INCOR Sao Paulo | Marcelo Franken | BRAZIL | Sao Paulo | Sao Paulo |
| Hospital das Clinicas - UFRGS | Marco Wainstein | BRAZIL | Porto Alegre | Porto Alegre |
| Hospital de Base de Sao Jose do Rio Preto | Lilia Maia | BRAZIL | Sao Jose do Rio Preto | Sao Jose do Rio Preto |
| Hospital de Messejana Dr. Carlos Alberto Studart Gomes | Frederico Augusto Silva | BRAZIL | Fortaleza | Fortaleza |
| Hospital e Maternidade Celso Pierro - PUCCamp | Jose Francisco Saraiva | BRAZIL | Campinas | Campinas |
| Hospital Felicio Rocho | Jamil Saad | BRAZIL | Belo Horizonte | Belo Horizonte |
| Hospital Mae de Deus | Euler Roberto Manenti | BRAZIL | Porto Alegre | Porto Alegre |
| Hospital Nossa Senhora da Conceicao | Pedro Pimentel Filho | BRAZIL | Porto Alegre | Porto Alegre |
| Hospital Sao Lucas - PUCRS | Luiz Carlos Bodanese | BRAZIL | Porto Alegre | Porto Alegre |
| Saint Vincent de Paul Hospital. | Rogerio Tumelero | BRAZIL | Passo Fundo | Passo Fundo |
| Hospital Universitario Walter Cantidio - UFC | Ricardo Silva | BRAZIL | Fortaleza | Fortaleza |
| Instituto de Cardiologia de Santa Catarina - ICSC | Artur Herdy | BRAZIL | Sao Jose | Sao Jose |
| Instituto de Cardiologia do Rio Grande do Sul | Oscar Dutra | BRAZIL | Porto Alegre | Porto Alegre |
| Instituto de Molestias Cardiovasculares - IMC | Wilma Roberta Ardito | BRAZIL | Sao Jose do Rio Preto | Sao Jose do Rio Preto |
| Instituto do Coracao do Triangulo Mineiro | Roberto Botelho | BRAZIL | Uberlandia | Uberlandia |
| Instituto Nacional de Cardiologia | Jose Geraldo Amino | BRAZIL | Rio de Janeiro | Rio de Janeiro |
| Intercath, Hospital Meridional | Jose Airton Arruda | BRAZIL | Cariacica | Cariacica |
| Natal Hospital Center | Maria Paiva | BRAZIL | Natal | Natal |
| Nucleo de Pesquisa Clinica | Paulo Roberto Rossi | BRAZIL | Curitiba | Curitiba |
| Pronto Socorro Cardiologico de Pernambuco-Prof. Luiz Tavares | Audes Diogenes Feitosa | BRAZIL | Recife | Recife |
| Santa Casa de Misericordia de Curitiba | Jose Augusto Fortes | BRAZIL | Curitiba | Curitiba |
| Santa Casa de Misericordia de Porto Alegre | Paulo Leaes | BRAZIL | Porto Alegre | Porto Alegre |
| Universidade Federal do Mato Grosso do Sul; Hospital Universitario | Delcio Silva Junior | BRAZIL | Campo Grande | Campo Grande |
| Cambridge Cardiac Care | A. Shekhar Pandey | CANADA | Cambridge | Cambridge |
| Canadian Centre for Research on Diabetes | James Conway | CANADA | Smiths Falls | Smiths Falls |
| Capital Health; QEII HSC; Oncology | Lawrence Title | CANADA | Halifax | Halifax |
| Centre de Dépistage et recherche cardiovasculaire Rive-Sud | Jean-Pierre Lavoie | CANADA | Longueuil | Longueuil |
| Centre de Sante et de Services sociaux de Chicoutimi | Gerald Tremblay | CANADA | Chicoutimi | Chicoutimi |
| Centre de santé et de services sociaux de Laval Hopital de la Cité de la Santé | Annie Roy | CANADA | LAVAL | LAVAL |
| Centre de Santé et des services sociaux de la Haute Yamaska | Philippe Robichaud | CANADA | Granby | Granby |
| Centre Hospitalier Pierre-LeGardeur | Denis Carl Phaneuf | CANADA | Terrebonne | Terrebonne |
| Centre Hospitalier Regional de Trois Rivieres Pavillon Ste-Marie | Ariel Horacio Diaz | CANADA | Trois-Rivieres | Trois-Rivieres |
| Centre Hospitalier Universitaire de Sherbrooke | Serge Lepage | CANADA | SHERBROOKE | SHERBROOKE |
| Clinique de Cardiologie de Lévis | Michel DeGrace | CANADA | Lévis | Lévis |
| Clinique Medicale des Trois Lacs | Christian Leduc | CANADA | Vaudreuil-Dorion | Vaudreuil-Dorion |
| Clinique Médicale Langelier | Guiseppe Mazza | CANADA | St-Léonard | St-Léonard |
| C&L RESEARCH | Maynard Luterman | CANADA | FORT EIRE | FORT EIRE |
| Cowan Topsail Medical Clinic | Anthony Rolfe | CANADA | St Johns | St Johns |
| CSSS du Nord de Lanaudière | Simon Kouz | CANADA | St-Charles-Borromée | St-Charles-Borromée |
| CSSS Vallee de l Or | Joel Pouliot | CANADA | Val DOr | Val DOr |
| Dr. Gregory Searles Clinic | Gregory Searles | CANADA | Saint John | Saint John |
| Dr M.P.J. Senaratne Professional Corporation | Manohara Senaratne | CANADA | Edmonton | Edmonton |
| Dr R. Labonté Professional Medicine Corporation | Roger Labonté | CANADA | Sudbury | Sudbury |
| Dr Saul Vizel Cardiac Research Office | Saul Vizel | CANADA | Cambridge | Cambridge |
| Fraser Clinical Trials Inc. | Dennis Rupka | CANADA | New Westminster | New Westminster |
| G.A. Research Associates Ltd. | Ronald Bourgeois | CANADA | Moncton | Moncton |
| GS Cardiac Lab Medicine Professional Corp | Gurcharan Syan | CANADA | Sudbury | Sudbury |
| Hamilton Health Sciences - General Site | Eva Lonn | CANADA | HAMILTON | HAMILTON |
| Heart Health and Exercise Laboratory | Robert Petrella | CANADA | London | London |
| Hospital du Sacré-Coeur de Montreal | Erick Schampaert | CANADA | Montreal | Montreal |
| Hopital Regional Dr. Georges L. Dumont | Jean-Francois Baril | CANADA | Moncton | Moncton |
| Hotel Dieu Hospital | Amer Johri | CANADA | KINGSTON | KINGSTON |
| Institut universitaire de cardiologie et de pneumologie de Québec (Hospital Laval) | Olivier Bertrand | CANADA | Ste. Foy | Ste. Foy |
| INTERMOUNTAIN RESEARCH CONSULTANTS | Frank Nigro | CANADA | Thunder Bay | Thunder Bay |
| JBN MEDICAL DIAGNOSTIC SERVICES INC. | JOSEPH BERLINGIERI | CANADA | Burlington | Burlington |
| LONDON HEALTH SCIENCES CENTRE | Shahar Lavi | CANADA | London | London |
| McGill University; Montreal General Hospital; Cardiovascular and Metabolic | THAO HUYNH | CANADA | Montreal | Montreal |
| Medi-Recherche Inc. | Daniel Savard | CANADA | Montréal | Montréal |
| Montreal Heart Institute | Jean Claude Tardif | CANADA | Montreal | Montreal |
| Newmarket Cardiology Research Group | Thangaroopan Molly | CANADA | Newmarket | Newmarket |
| OSHAWA CLINIC | Asaad Bakbak | CANADA | OSHAWA | OSHAWA |
| Peel Research Associates | Laurie Hill | CANADA | Brampton | Brampton |
| Philippe R. Beaudry Medicine Professional Corporation | Philippe Beaudry | CANADA | Burlington | Burlington |
| Q and T Research Outaouais Inc | Patrice Nault | CANADA | Gatineau | Gatineau |
| QUEEN ELIZABETH HOSPITAL | Patrick Bergin | CANADA | Charlottetown | Charlottetown |
| Recherche Clinique Sigma Inc. | Guy Chouinard | CANADA | Quebec city | Quebec city |
| Recherche Médicale St-Jérome Inc. | YVES PESANT | CANADA | ST-JEROME | ST-JEROME |
| Recherches Cliniques Theradev | Didier Fay | CANADA | Granby | Granby |
| Red Deer Regional Hospital | Jorge Nogareda | CANADA | Red Deer | Red Deer |
| Royal Alexandra Hospital | Raymond Leung | CANADA | Edmonton | Edmonton |
| South Shore Medical Arts | Ron James Hatheway | CANADA | Bridgewater | Bridgewater |
| St. Mary's General Hospital | Stuart Smith | CANADA | Kitchener | Kitchener |
| ST. MICHAEL'S HOSPITAL | Beth Abramson | CANADA | TORONTO | TORONTO |
| SUDBURY REGIONAL HOSPITAL | Shah Nawaz | CANADA | SUDBURY | SUDBURY |
| Surrey Memorial Hospital; SMH Cardiology Clinical Trials Inc | Jan Kornder | CANADA | Surrey | Surrey |
| University of Alberta Hospital | Robert Welsh | CANADA | Edmonton | Edmonton |
| ViaCar recherche Clinique Inc. | Raja Chehayeb | CANADA | Greenfield Park | Greenfield Park |
| General Teaching Hospital Prague;Dept. of Internal Medicine II Cardiology and Angiology | Jan Belohlavek | CZECH REPUBLIC | Prague 2 | Prague 2 |
| General University Hospital | Jan Malik | CZECH REPUBLIC | PRAGUE 2 | PRAGUE 2 |
| Hospital Kladno | Ivo Podpera | CZECH REPUBLIC | Kladno | Kladno |
| IKEM | Jiri Kettner | CZECH REPUBLIC | Prague | Prague |
| Interni Ambulance | Richard Ferkl | CZECH REPUBLIC | Trutnov | Trutnov |
| Nemocnice Tabor, a.s. | Rostislv Kral | CZECH REPUBLIC | Tabor | Tabor |
| Nemocnice Znojmo | Zdenek Monhart | CZECH REPUBLIC | Znojmo | Znojmo |
| St. Anne's University Hospital; 1st Cardioangiological Clinic | Martin Novak | CZECH REPUBLIC | BRNO | BRNO |
| University Hospital Hradec Kralove; Department of Internal Medicine | Miroslav Solar | CZECH REPUBLIC | Hradec Kralove | Hradec Kralove |
| University Hospital Olomouc; 1st Dept. of Internal Medicine/Cardiology | Martin Hutyra | CZECH REPUBLIC | Olomouc | Olomouc |
| Fredericia Sygehus | Thomas Gohr | DENMARK | Fredericia | Fredericia |
| Regionshospitalet Herning, Hjertemedicinsk Afsnit | Ole May | DENMARK | Herning | Herning |
| Rigshopitalet, Copenhagen University Hospital; Department of Cardiology | Peter Clemmensen | DENMARK | Copenhagen | Copenhagen |
| Slagelse Sygehus | Jens Lomholdt | DENMARK | Slagelse | Slagelse |
| Cardiologie Sud; Coronarographie | Marine Verges | FRANCE | Montpellier | Montpellier |
| CENTRE HOSPITALIER DE LAGNY; SERVICE DE CARDIOLOGIE | Simon Elhadad | FRANCE | LAGNY-SUR-MARNE | LAGNY-SUR-MARNE |
| Centre Hospitalier de Valenciennes, Nouvel Hopital; Cardiologie, Unite de Soins Intensifs | Benaissa Agraou | FRANCE | Valenciennes | Valenciennes |
| CHU de Nantes - Hopital Laennec | Vincent Probst | FRANCE | Boulevard Jacques Monod | Boulevard Jacques Monod |
| CHU Rangueill; Service de Cardiologie | Michel Galinier | FRANCE | Toulouse | Toulouse |
| Expl Fonct Cardiovasculaire;Hopital De Jour De Cardiologie | Michel Ovize | FRANCE | Bron | Bron |
| Fondation Hopital Saint Joseph;Cardiologie Clinique | Fabrice D Houdain | FRANCE | Marseille | Marseille |
| HEGP Paris; Service de cardiologie | Nicolas Danchin | FRANCE | PARIS | PARIS |
| Hospital Cardiologique de Haut Leveque | Raymond Pierre Roudaut | FRANCE | Pessac | Pessac |
| Hospital du Bocage; Centre de Cardiologie | Yves Cottin | FRANCE | Dijon | Dijon |
| Hospital Henri Mondor | Anne Isabelle Tropeano | FRANCE | Creteil | Creteil |
| Hospital Marie Lannelongue | Christophe Caussin | FRANCE | Le Plessis Robinson | Le Plessis Robinson |
| Hopital Pitié Salpetriere; Département de cardiologie | Gilles Montalescot | FRANCE | PARIS | PARIS |
| Hopitaux de Chartres | Teodora Dutoiu | FRANCE | LE COUDRAY | LE COUDRAY |
| Hospital of Cambrai | Abdelkader Belhassane | FRANCE | Cambrai | Cambrai |
| Public Hospital; CHU Jean Minjor Service De Cardiologie | Francois Schiele | FRANCE | Besancon | Besancon |
| Asklepios Klinik St. Georg; Cardiology | MARTIN BERGMANN | GERMANY | Hamburg | Hamburg |
| Berufsgenossenschaftliches Uni-Klinikum Bergmannsheil GmbH | Andreas Muegge | GERMANY | Bochum | Bochum |
| CAPRaIS-Dr. M. Natour | Mohammed Natour | GERMANY | Heidelberg | Heidelberg |
| Charite Campus Benjamin Franklin | Carsten Tschope | GERMANY | Berlin | Berlin |
| Charité Campus Virchow-Klinikum; Department of Cardiology | Hans-Dirk Dungen | GERMANY | Berlin | Berlin |
| DEUTSCHES HERZZENTRUM BERLIN | Eckart Fleck | GERMANY | Berlin | Berlin |
| DRK Kliniken Berlin Kopenick | Hans-Friedrich Voehringer | GERMANY | Berlin | Berlin |
| Heart and Diabetes Center North Rhine-Westphalia | Siegfried Eckert | GERMANY | Bad Oeynhausen | Bad Oeynhausen |
| Herz-und Kreislaufzentrum Rotenburg; Institut fur Klinische Forschung | Klaus Edel | GERMANY | Rotenburg | Rotenburg |
| HERZZENTRUM BAD KROZINGEN | Franz-Josef Neumann | GERMANY | BAD KROZINGEN | BAD KROZINGEN |
| Kardiologische praxis Nienburg | Nicolaos Proskynitopoulos | GERMANY | Nienburg | Nienburg |
| Kerckhoff Heart and Thorax Center; Cardiology | Christian Hamm | GERMANY | Bad Nauheim | Bad Nauheim |
| Klinik Am See | Heinz Voeller | GERMANY | Ruedersdorf | Ruedersdorf |
| Kliniken Maria Hilf GmbH, Krankenhaus St. Franziskus | Juergen Vom Dahl | GERMANY | MüNCHENGLADBACH | MüNCHENGLADBACH |
| KLINIK HANNOVER NORDSTADT; MEDIZINISCHE KLINIK | JOHANNES HENSEN | GERMANY | HANNOVER | HANNOVER |
| Klinikum Frankfurt HOchst GmbH | Christoph Kadel | GERMANY | Frankfurt am Main | Frankfurt am Main |
| VOLKER SCHaCHINGER | VOLKER schachinger | GERMANY | Fulda | Fulda |
| Klinikum Innenstadt Medizinische Klinik Abt.Kardiologie u.Angiologie | Hae Young Sohn | GERMANY | Muenchen | Muenchen |
| KLINIKUM PIRNA GMBH | Peter Michalko | GERMANY | PIRNA | PIRNA |
| Maria Heimsuchung Caritas-Klinik Pankow | Thomas Ali | GERMANY | Berlin | Berlin |
| MediClin Herzzentrum Lahr-Baden | Eberhardvon Hodenberg | GERMANY | Lahr | Lahr |
| Mediclin Rehazentrum Spreewald | Wolfram Kamke | GERMANY | Burg | Burg |
| Praxis Dr. Kühne | Ursula Kühne | GERMANY | Berlin | Berlin |
| Universitaetsklinikum des Saarlandes; Klinik f. Innere Medizin III | Ulrich Laufs | BULGARIA | Plovdiv | Plovdiv |
| 波恩大学医院心内科 | Nikos Werner | GERMANY | Bonn | Bonn |
| 明斯特大学医院 | Holger Reinecke | GERMANY | Münster | Münster |
| 约翰内斯·古腾堡大学医学 | Thomas Münzel | GERMANY | Mainz | Mainz |
| University Hospital Duesseldorf | Malte Kelm | GERMANY | Düsseldorf | Düsseldorf |
| University Medical Centre Mannheim; 1st Medical Department | Ursula Hoffmann | GERMANY | Mannheim | Mannheim |
| University of Cologne | Hannes Reuter | GERMANY | Koeln | Koeln |
| B-A-Z County Hospital | Kálmán Csapó | HUNGARY | Miskolc | Miskolc |
| DRUG RESEARCH CENTER KFT | LASZLO KORANYI | HUNGARY | BALATONFUERED | BALATONFUERED |
| Fejér Megyei Szent Gyorgy Kórház ; Cardio Logic Department | Matyas Sereg | HUNGARY | Székeshehérvár | Székeshehérvár |
| Gottsegen Gyorgy Országos Kardiológiai Intézet | Gabriella Hodi | HUNGARY | Budapest | Budapest |
| Hetenyi Geza County Hospital; Onkologiai Kozpont | Bela Benczur | HUNGARY | Szolnok | Szolnok |
| Kaposi Mor Teaching Hospital | László Deák | HUNGARY | Kaposvár | Kaposvár |
| Markusovszky Hospital | Lajos Nagy | HUNGARY | SZOMBATHELY | SZOMBATHELY |
| Outpatient Clinic of Debrecen | István Czuriga | HUNGARY | Debrecen | Debrecen |
| Pandy Gyula Hospital | Mihaly Dudas | HUNGARY | GYULA | GYULA |
| PTE AOK Szívgyógyászati Klinika | Ivan Horvath | HUNGARY | Pécs | Pécs |
| Semmelweis Egyetem, II. Belgyógyászati Klinika | ANIKO SOMOGYI | HUNGARY | Budapest | Budapest |
| Szent Istvan és Szent Laszlo Hospital | Andras Vertes | HUNGARY | Budapest | Budapest |
| Szt Rókus Hospita; Cardiological Rehabilitation Dept | András Papp | HUNGARY | BUDAPEST | BUDAPEST |
| University of Debrecen Medical and Health Science Center, Institute of Internal medicine Building B | ISTVAN EDES | HUNGARY | DEBRECEN | DEBRECEN |
| Zala megyei onkormányzat Kórház és Rendelointézet | Géza Lupkovics | HUNGARY | Zalaegerszeg | Zalaegerszeg |
| Amrita Institute of Medical Sciences | Ambika Unnikrishnan | INDIA | Kochi | Kochi |
| Arneja Heart Institute | Jaspal Arneja | INDIA | Nagpur | Nagpur |
| Artemis Health Institute | Dheeraj Kapoor | INDIA | Gurgaon | Gurgaon |
| Asian Heart Institute | Tilak Suvarna | INDIA | Mumbai | Mumbai |
| Belgaum Diabetes Centre | Neeta Deshpande | INDIA | Belgaum | Belgaum |
| Care Hospital | Bipin Sethi | INDIA | Hyderabad | Hyderabad |
| City Diagnostics | Ashok Dash | INDIA | Hyderabad | Hyderabad |
| Dr.Modi's Clinic | Byrapaneni Babu | INDIA | Hyderabad | Hyderabad |
| Gandhi's Research institute | Pramod Gandhi | INDIA | Nagpur | Nagpur |
| Ganga Ram Hospital; Dharma Vira Heart Centre | Purshottam Khanna | INDIA | New Delhi | New Delhi |
| Global Hospital & Health City | Guru Prasad | INDIA | Chennai | Chennai |
| Institute of Post Graduate Medical Education And Research | Subhankar Chowdhury | INDIA | Kolkata | Kolkata |
| JSS Hospital, MG road Mysore | Hathur Gowdappa | INDIA | Mysore | Mysore |
| Kasturba Medical College & Hospital | Prabha Adhikari | INDIA | mangalore | mangalore |
| KEM Hospital | Milind Gadkari | INDIA | Pune | Pune |
| KLES Dr. Prabhakar KORE Hospital and Medical Research Centre; Clinical Research Center (CRC) | Mallikarjun Jali | INDIA | Belgaum | Belgaum |
| Krishna Institute of Medical Science | Rajendra Premchand | INDIA | Secunderabad | Secunderabad |
| Lakeshore Hospital and Research Centre | Johny Kannampilly | INDIA | Kochi | Kochi |
| Life Care institute of Medical Sciences and Research | Sameer Dani | INDIA | Ahmedabad | Ahmedabad |
| Lotus diagnostic Centre | Arpandev Bhattacharya | INDIA | Bangalore | Bangalore |
| Mahavir hospital and research center | Shiva Yerra | INDIA | Hyderabad | Hyderabad |
| Mediciti hospital | Rakesh Sahay | INDIA | Hyderabad | Hyderabad |
| Meenakshi Mission Hospital and Research Centre | Selvamani Setthuraman | INDIA | Madhurai | Madhurai |
| Monilek Hospital And Research Centre | Mukesh Sarna | INDIA | Jaipur | Jaipur |
| Narayana Hrudayalaya Institute of Medical Science | Sanjay Mehrotra | INDIA | Bangalore | Bangalore |
| Palakkad Diabetic Centre, SMO Connect | Radhakrishnan Pathanakayil | INDIA | Palakkad | Palakkad |
| Poona Hospital and Research Centre | Jagdish Hiremath | INDIA | Pune | Pune |
| Radiance Hospital | Anil Jawahirani | INDIA | Nagpur | Nagpur |
| RUBY HALL CLINIC | Suhas Hardas | INDIA | Pune | Pune |
| Sanjay Gandhi Post Graduate Institute of Medical Sciences; Department of Cardiology | Sudeep Kumar | INDIA | Lucknow | Lucknow |
| Sanjivani Super Speciality Hospital Pvt Ltd | Kamal Sharma | INDIA | Ahmedabad | Ahmedabad |
| Sheth Shri Pukhraj Raichand Hospital | Subir Ghosh | INDIA | Ahmedabad | Ahmedabad |
| St johns Medical College and Hospital | Ganapathi Bantwal | INDIA | Bangalore | Bangalore |
| Suyash Hospital Pvt. Ltd. | Govind Malpani | INDIA | Indore | Indore |
| The Heart Care Clinic | Keyur Parikh | INDIA | Ahmedabad | Ahmedabad |
| Unity Hospital and Medicity Heart Care | Yusuf Kumble | INDIA | Mangalore | Mangalore |
| AMNCH (Adelaide and Meath National Children's Hospital); Cardiology Department | Vincent Maher | IRELAND | Tallaght Dublin | Tallaght Dublin |
| Beaumont Hospital; Cardiology Department | Brendan McAdam | IRELAND | DUBLIN | DUBLIN |
| Mater Misericordiae University Hospital; Department of Cardiology | Declan Sugrue | IRELAND | Dublin | Dublin |
| Portiuncula Hospital, Ballinasloe;Cardiac Research Dept. | John Barton, Jr. | IRELAND | Ballinasloe | Ballinasloe |
| St James Hospital; Cardiac Research | Peter Crean | IRELAND | Dublin | Dublin |
| University College Hospital | Briain Macneill | IRELAND | GALWAY | GALWAY |
| Azienda Ospedaliera S. Maria della Misericordia; Dipartimento di Cardiologia | Giorgio Morocutti | ITALY | Udine | Udine |
| Azienda Ospedaliera Universitaria Arcispedale S. Anna | Marco Valgimigli | ITALY | FERRARA | FERRARA |
| Azienda S. Maria Nuova | Giovanni Tortorella | ITALY | Reggio Emilia | Reggio Emilia |
| Bentivoglio Hospital - Azienda USL di Bologna; Cardiology Unit | Leonardo Pancaldi | ITALY | Bentivoglio | Bentivoglio |
| Centro Cardiologico Monzino, IRCCS | Alessandro Salvioni | ITALY | Milano | Milano |
| Fondazione IRCCS Policlinico San Matteo | Ezio Bramucci | ITALY | PAVIA | PAVIA |
| Hospital Niguarda | Antonio Mafrici | ITALY | MILANO | MILANO |
| Ospedale A. Poma | Roberto Zanini | ITALY | Mantova | Mantova |
| Ospedale Civile di Legnano | Stefano De Servi | ITALY | LEGNANO | LEGNANO |
| Ospedale Santa Maria della Misericordia | Loris Roncon | ITALY | ROVIGO | ROVIGO |
| Ospedale S. Maria della Misericordia; Struttura Complessa di Cardiologia | Claudio Cavallini | ITALY | Perugia | Perugia |
| Ospedale S. Maria delle Grazie | Vincenzo Grassia | ITALY | POZZUOLI | POZZUOLI |
| Ospedali Riuniti di Bergamo | Giuseppe Musumeci | ITALY | BERGAMO | BERGAMO |
| Sapienza University; Dept. of Cardiology | Francesco Consentino | ITALY | Rome | Rome |
| Universita Federico II | Pasquale Perrone Filardi | ITALY | NAPOLI | NAPOLI |
| Ajou University Hospital | Seung Jea Tahk | KOREA | Suwon City | Suwon City |
| Boramae Hos | Kim Sang-Hyun | KOREA | Seoul | Seoul |
| Bucheon St Mary's hospital | Hee Yeol Kim | KOREA | Gyemggi-do | Gyemggi-do |
| CHONBUK NATIONAL UNI HOSPITAL | Jae Keon Chae | KOREA | Jeonju | Jeonju |
| Chonnam National University Hospital | Myung-ho Jeong | KOREA | Gwang Ju | Gwang Ju |
| Chung-Ang University Hospital | Sang-Wook Kim | KOREA | Seoul | Seoul |
| Chungnam National University Hospital | Jin-Ok Jeong | KOREA | Daejeon | Daejeon |
| Gil Hospital. Gachon University | Woong Chol Kang | KOREA | Incheon | Incheon |
| Hallym University Medical Center, Kangnam Sacred Heart Hospital | Namho Lee | KOREA | Seoul | Seoul |
| HALLYM UNIVERSITY SACRED HEART HOSPITAL | Woo Jung Park | KOREA | GYEONGGI-DO | GYEONGGI-DO |
| Inha Univ. Hospital; Cardiology Department | Keum Soo Park | KOREA | Incheon | Incheon |
| Inje University Busan Paik Hospital | Kim Dae Kyeong | KOREA | Busan | Busan |
| Inje University Ilsan Paik Hospital | Sung Yun Lee | KOREA | Goyang | Goyang |
| Keimyung University Dongsan Medical Center | Seung-Ho Hur | KOREA | DAEGU | DAEGU |
| Korea University Guro Hospital | Chang Gyu Park | KOREA | Gurogu | Gurogu |
| Korea University Medical Ceter | Do Sun Lim | KOREA | Seoul | Seoul |
| Kosin University Gospel Hospital | Tae-Joon Cha | KOREA | Busan | Busan |
| KyungHee Medical Center | Weon Kim | KOREA | Seoul | Seoul |
| NHIC Ilsan Hospital | Dong-Woon Jeon | KOREA | Kyonggi-do | Kyonggi-do |
| Pusan University Hospital | Taekjong Hong | KOREA | Busan | Busan |
| Seoul National University Hospital | Hyo-Soo Kim | KOREA | Seoul | Seoul |
| Soonchunhyang University Hospital; Cardiology, Department of Internal Medicine | Min-Su Hyon | KOREA | Seoul | Seoul |
| St. Vincent's Hospital | Keon-Woong Moon | KOREA | Suwon | Suwon |
| Uijongbu St.Mary's Hospital, The Catholic University of Korea | Hui-Kyung Jeong | KOREA | Uijongbu | Uijongbu |
| Ulsan University Hosiptal | Sang-Kon Lee | KOREA | Ulsan | Ulsan |
| Yeungnam Univ. Hospital | Jond-Seon Park | KOREA | Daegu | Daegu |
| Yonsei University Wonju College of Medicine | Junghan Yoon | KOREA | Kangwon-Do | Kangwon-Do |
| Hospital Raja Perempuan Zainab II | Mansour Yahya | KOREA | Kota Bharu | Kota Bharu |
| Hospital Serdang | Abd Kahar Abd Ghapar | MALAYSIA | Serdang | Serdang |
| Hospital Tengku Ampuan Afzan; Cardiology Department | Kok Huan Ng | MALAYSIA | Kuantan | Kuantan |
| Institut Jantung Negara Malaysia | Rosli Ali | MALAYSIA | Kuala Lumpur | Kuala Lumpur |
| Penang Hosptial; Cardiology Department | Omar Ismail | MALAYSIA | Penang | Penang |
| Sarawak General Hospital; Department of Radiotherapy, Oncology and Palliative care | Tiong Kiam Ong | MALAYSIA | Kuching | Kuching |
| University Malaya Medical Center | Wan Azman Wan Ahmad | MALAYSIA | Kuala Lumpur | Kuala Lumpur |
| HOSPITAL UNIVERSITI SAINS; HEALTH CAMPUS | DATO' MAFAUZY MOHAMED | MALAYSIA | KELANTAN | KELANTAN |
| ALTHIAN RESEARCH CENTER | Manuel Guerrero-Garza | MEXICO | MONTERREY | MONTERREY |
| Cardiolink Clin Trials | Armando Garcia Castillo | MEXICO | Monterrey | Monterrey |
| CARDIOPREVENT SC | Roxana Reyes Sanchez | MEXICO | DURANGO | DURANGO |
| Cent de Inv Cientifica del Estado de Chihuahua | Luis Ruiz | MEXICO | Chihuahua | Chihuahua |
| CENTRO DE ESPECIALIDADES MEDICAS DEL ESTADO DE VERACRUZ | ENRIQUE LóPEZ ROSAS | MEXICO | XALAPA | XALAPA |
| Centro De Estudios De Investigacion Metabolicos Y Cariovasculares SC | RAFAEL VIOLANTE | MEXICO | Tamaulipas | Tamaulipas |
| Centro de Investigacion; Clinica Del Pacifico | Jesus Hernandez-Munuzuri | MEXICO | Acapulco | Acapulco |
| CENTRO ESPECIALIZADO EN DIABETES; INVESTIGACIóN DIABETES | MELCHOR ALPIZAR-SALAZAR | MEXICO | MEXICO CITY | MEXICO CITY |
| CENTRO MéDICO LUCERNA | ARTURO GUERRA | MEXICO | TIJUANA | TIJUANA |
| CENTRO PARA EL DESARROLLO DE LA MEDICINA Y DE ASISTENCIA | CARLOS HERNANDEZ | MEXICO | MONCLOVA | MONCLOVA |
| CENTRO PARA EL DESARROLLO DE LA MEDICINA Y DE ASISTENCIA | MANUEL ODIN DE LOS RIOS IBARRA | MEXICO | Culiacan | Culiacan |
| Clinical Research Institute | Daniel Micher | MEXICO | Tlalnepantla | Tlalnepantla |
| Clinicals Trials Mexico | Alejandro Lechuga | MEXICO | PACHUCA | PACHUCA |
| CLINICA OMEGA (CENTRO DE ATENCIóN E INVESTIGACIóN CARDIOVASCULAR) | HECTOR SANCHEZ | MEXICO | Mexico City | Mexico City |
| FUNDACIóN CARDIOVASCULAR DE AGUASCALIENTES | EDMUNDO BAYRAM | MEXICO | AGUASCALIENTES | AGUASCALIENTES |
| Global Trial Research | Ciro Riojas | MEXICO | Monterrey | Monterrey |
| HOSPITAL ANGELES DEL PEDREGAL | Jose Cervantes | MEXICO | MEXICO CITY | MEXICO CITY |
| HOSPITAL CARDIOLOGICA AGUASCALIENTES | GUILLERMO LLAMAS | MEXICO | AGUASCALIENTES | AGUASCALIENTES |
| HOSPITAL CENTRAL DR. IGNACIO MORONES PRIETO | JOSE LEIVA PONS | MEXICO | SAN LUIS POTOSI | SAN LUIS POTOSI |
| HOSPITAL CENTRAL UNIVERSITARIO | CEDEnO RODOLFO | MEXICO | CHIHUAHUA | CHIHUAHUA |
| Hospital Dr. Angel Leano | Raul Velasco-Sanchez | MEXICO | Zapopan | Zapopan |
| HOSPITAL GENERAL DE DURANGO | LUIS ZAVALA FERNáNDEZ | MEXICO | DURANGO | DURANGO |
| Hospital General De Puebla Dr. Eduardo Vazquez Navarro | Juan Carlos Alva | MEXICO | PUEBLA | PUEBLA |
| HOSPITAL METROPOLITANO | ROBERTO QUIROGA | MEXICO | MONTERREY | MONTERREY |
| Hospital Regional Veracruz/FIMBIO | Homero Guzman | MEXICO | Veracruz | Veracruz |
| HOSPITAL UNI; DR. JOSE E. GONZALEZ | MARIO BENAVIDES | MEXICO | Monterrey | Monterrey |
| ICLE S.C | ERNESTO CARDONA MUnOZ | MEXICO | GUADALAJARA | GUADALAJARA |
| Instituto Biomedico De Investigacion A.C. | Jose Ramirez Isunza | MEXICO | Aguascalientes | Aguascalientes |
| Instituto De Corazon De Queretaro | Marco Alcocer Gamba | MEXICO | Queretaro | Queretaro |
| Instituto De Diabetse Y Riesgo Cardiovascular S.A. De C.V. | Jorge Guillermo Chavez Paez | MEXICO | Puerto Vallarta | Puerto Vallarta |
| Instituto Nacional de Cardiologia Ignacio Chavez | Enrique Mendoza Perez | MEXICO | MEXICO CITY | MEXICO CITY |
| MEDICA SUR | Emma Miranda Malpica | MEXICO | MEXICO CITY | MEXICO CITY |
| PRIVATE MEDICAL OFFICE | GABRIELRA MOS LOPEZ | MEXICO | GUADALAJARA | GUADALAJARA |
| Unidad de patologia clinica | Rosario Arechavaleta Grranell | MEXICO | Guadalajara | Guadalajara |
| UNIDAD DE INVESTIGACIóN EN SALUD | LEOCADIO MUnOZ | MEXICO | CIUDAD JUáREZ | CIUDAD JUáREZ |
| Academisch Medisch Centrum Universiteit Amsterdam | ROBBERT DE WINTER | NETHERLANDS | AMSTERDAM | AMSTERDAM |
| Isala Klinieken | Arnoud W.J. van 't Hof | NETHERLANDS | ZWOLLE | ZWOLLE |
| L.U.M.C./ Cardiology | J.W.Jukema | NETHERLANDS | LEIDEN | LEIDEN |
| ONZE LIEVE VROUWE GASTHUIS | Johannes Paulus Remigius Herrman | NETHERLANDS | AMSTERDAM | AMSTERDAM |
| SLOTERVAART ZIEKENHUIS | VICTOR GERDES | NETHERLANDS | Amsterdam | Amsterdam |
| ST. ANTONIUS ZIEKENHUIS NIEUWEGEIN; R&D CARDIOLOGY | Jurrin M. ten Berg | NETHERLANDS | NIEUWEGEIN | NIEUWEGEIN |
| UMC ST RADBOUD; INWENDIGE ZIEKTEN | Anton F.H. Stalenhoef | NETHERLANDS | NIJMEGEN | NIJMEGEN |
| Vasculair Onderzoek Centrum Hoorn BV | Dick C. G.Basart | NETHERLANDS | Hoorn | Hoorn |
| Waterland Ziekenhuis | Marcel J.J.A.Bokern | NETHERLANDS | Purmerend | Purmerend |
| Zaans Medisch Centrum | Patrick N. A.Bronzwaer | NETHERLANDS | Zaandam | Zaandam |
| Christ Church Cardioendcrine Research Group; Department of Medicine | Richard Troughton | NEW ZEALAND | Christchurch | Christchurch |
| Hutt Valley District Health Board | Timothy O'Meeghan | NEW ZEALAND | Christchurch | Christchurch |
| Hutt Valley District Health Board | Timothy O'Meeghan | NEW ZEALAND | Lower Hutt | Lower Hutt |
| Middlemore Hospital | Selwyn Wong | NEW ZEALAND | Auckland | Auckland |
| Nelson Hospital | Andrew Hamer | NEW ZEALAND | Nelson | Nelson |
| Palmerston North Hospital, MidCentral DHB; Cardiology Department | Eng Wei (Dave) Tang | NEW ZEALAND | Palmerston North | Palmerston North |
| Tauranga Hospital; Bay of Plenty Med Rsrch | Balaratnam Nirmalaraj | NEW ZEALAND | Tauranga | Tauranga |
| 4th Military Hospital. Centre for Heart Disease; Department of Cardiology | Piotr Ponikowski | POLAND | Wroclaw | Wroclaw |
| Amamed NZOZ Warszawa | Maciej Olszewski | POLAND | Warszawa | Warszawa |
| American Heart of Poland | Pawel Buszman | POLAND | Ustron | Ustron |
| Central Clinical Hospital Military Medical Institute; Cardiology Department | Andrzej Cwetsch | POLAND | Warszawa | Warszawa |
| Centrum Szybkiej Diagnostyki Kardiologicznej Kardiomed | Maciej Zabowka | POLAND | Tarnów | Tarnów |
| Gabinet Kardiologiczno-Internistyczny | Marek Piepiorka | POLAND | Gdynia | Gdynia |
| Gabinet Kardiologiczny Medipuls | Pawel Miekus | POLAND | Gdynia | Gdynia |
| II Oddzia Kardiologiczny, American Heart of Poland | Bogdan Gorycki | POLAND | Bielsko-Biala | Bielsko-Biala |
| IV Oddzia Kardiologii Inwazyjnej, American Heart of Poland | Janusz Prokopczuk | POLAND | Kedzierzyn-Kozle | Kedzierzyn-Kozle |
| Katedra Kardiologii Kardiochirurgii Uniwersytet Medyczny w ￡odzi | Maciej Kosmider | POLAND | Lodz | Lodz |
| Klinika Choroby Wiencowej. Instytut Kardiologii. warszawa | Hanna Szwed | POLAND | WARSAW | WARSAW |
| Klinika Kardiologii Uniwersytetu Medycznego W ￡Odzi | Maria KrzemiNska- Paku3a | POLAND | ￡ódx | ￡ódx |
| KO-Med Specjalistyczny Gabinet Lekarski | Marek Konieczny | POLAND | Pulawy | Pulawy |
| Medical University of Bialystok; Department of Cardiology | Wlodzimierz Musial | POLAND | BIALYSTOK | BIALYSTOK |
| Medical University of Warsaw, Poland; Invasive Cardiology Unit I Cardiac Department | Janusz Kochman | POLAND | WARSZAWA | WARSZAWA |
| NZOZ Przychodnia Lomzynska | Marian Krzyzanowski | POLAND | Bydgoszcz | Bydgoszcz |
| NZOZ Serafin-Med | Ryszard Serafin | POLAND | Zarow | Zarow |
| NZOZ Zdowie s.c. | Donald Drozdz | POLAND | Olesnica, Spalice | Olesnica, Spalice |
| Poliklinika Evi-Med Sp.z o.o. | Michal Szpajer | POLAND | Gdynia | Gdynia |
| Pope John Paul II Hosp; Dept. Cardiology | Andrzej Kleinrok | POLAND | Zamosc | Zamosc |
| Powiatowy Zespó3 Zk3adów Opieki Zdrowotnej Bêdzin | Maciej Hamankiewicz | POLAND | Bêdzin | Bêdzin |
| Private Healthcare Centre | Jerzy Kowalski | POLAND | Wola | Wola |
| Prywatny Gabinet Lekarski | Michal Ogorek | POLAND | Piotrkow Trybunalski | Piotrkow Trybunalski |
| Prywatny Gabinet Lekarski | Marianna Janion | POLAND | Kielce | Kielce |
| Prywatny Spescjalistyczny Gabinet Kardiologiczno - Internistyczny | Jacek Nowak | POLAND | Libiaz | Libiaz |
| Specialistic Hospital; Department of Internal Medicine | Szczuka Kazimierz | POLAND | gorlice | gorlice |
| Specjal.Gabinet Lek. Internist.-Kardiolog. | Boguslaw Derlaga | POLAND | Tarnow | Tarnow |
| Specjalistyczna Praktyka Lekarska Leszek Bryniarski | Leszek Bryniarski | POLAND | Krakow | Krakow |
| SP ZOZ w Swidnicy Regionalny Szpital Specjalistyczny LATAWIEC | Bartlomiej Janiak | POLAND | Swidnica | Swidnica |
| Szpital Kliniczny Przemienienia PaNskiego ; Uniwersytet w medyczny Poznaniu | Maciej Lesiak | POLAND | Poznan | Poznan |
| SZPITAL Rejonowy Kutno; III Odzial Chorob Wewnetrznych Poradnia Kardiologiczna | Tomasz Wierzykowski | POLAND | Kutno | Kutno |
| Szpital Wojewodzki No2; Oddzia3 Kardiologii | Jerzy Kuzniar | POLAND | Rzeszow | Rzeszow |
| Szpital Zachodni Grodzisk Mazowiecki; Dept. of Diagnostic Cardiology | Maciej Zarebinski | POLAND | Grodzisk Mazowiecki | Grodzisk Mazowiecki |
| Twoja Przychodnia | Zbigniew Pijanowski | POLAND | Lublin | Lublin |
| Unimed | Andrzej Ochala | POLAND | Katowice | Katowice |
| UNIVERSITY HOSPITAL; INTERNAL MEDICINE AND GERIATRICS | JOLANTA WALCZEWSKA | POLAND | KRAKOW | KRAKOW |
| Uniwersyteckie Centrum Medycyny Morskiej I Tropikalnej; Klinika Chor. Wewn. i Rehab. Kard. | Jacek Gorski | POLAND | Gdynia | Gdynia |
| UNIWERSYTET MEDYCZNY W LUBLINIE; KLINIKA KARDIOLOGII DZIECIECEJ | ANDRZEJ WYSOKINSKI | POLAND | Lublin | Lublin |
| Wielospecjalistyczny Szpital SP ZOZ w Nowej Soli; Oddzial Kardiologii | Jaroslaw Hiczkiewicz | POLAND | Nowa Sol | Nowa Sol |
| Wojewodzki Szpital Brodnowski; Klinika Kardiologii | Miroslaw Dluzniewski | POLAND | Warszawa | Warszawa |
| Wojewódzki Szpital Specjalistyczny Nr 4; Odzdzia3 Kardiologii | KuOEnierz Barbara | POLAND | Bytom | Bytom |
| Wojewódzki Szpital Zespolony, Oddzial Kardiologii | Krystyna Jaworska | POLAND | Torun | Torun |
| Wojewódzki Szpital Zespolony, Oddzial Kardiologii | Krzysztof Kuc | POLAND | Torun | Torun |
| WSS | Tomasz Dryja | POLAND | Zgorzelec | Zgorzelec |
| Zespol Opieki Zdrowotnej; Oddzial Chorob Wewnetrznych | Ryszard Sciborski | POLAND | Olawa | Olawa |
| ZOZ w Nysie, Szpital, Oddzial Internistyczno - Kardiologiczny | Miarka Jacek | POLAND | Nysa | Nysa |
| Cardio Med SRL | Imre Benedek | ROMANIA | Targu-Mures | Targu-Mures |
| CARDIOMED SRL | Constantin Militaru | ROMANIA | Craiova | Craiova |
| CMI Dr Morosanu Magdalena | MAGDALENA MOROSANU | ROMANIA | Galati | Galati |
| County Clinical Emergency Hospital Brasov | Mariana Radoi | ROMANIA | Targu-Mures | Targu-Mures |
| CARDIOMED SRL | Constantin Militaru | ROMANIA | Craiova | Craiova |
| CMI Dr Morosanu Magdalena | MAGDALENA MOROSANU | ROMANIA | Galati | Galati |
| County Clinical Emergency Hospital Brasov | Mariana Radoi | ROMANIA | Brasov | Brasov |
| County Clinical Emergency Hospital Cluj | Ioan Andrei Veresiu | ROMANIA | Cluj-Napoca | Cluj-Napoca |
| Emergency Clinical County Hospital | Amorin Remus Popa | ROMANIA | Oradea | Oradea |
| ILRO MEDICAL SRL | Ana-Gabriela Fruntelata | ROMANIA | Bucharest | Bucharest |
| O.D. Medica SRL | Simona Tivadar | ROMANIA | Bucharest | Bucharest |
| S.C.DIABMED DR. POPESCU ALEXANDRINA S.R.L. | ALEXANDRINA POPESCU | ROMANIA | PLOIESTI | PLOIESTI |
| SC MEDCON SRL | Silviana Constantinescu | ROMANIA | Buzau | Buzau |
| Timisoara Institute of Cardiovascular Diseases | Stefan Dragulescu | ROMANIA | Timisoara | Timisoara |
| Almazov Federal Heart, Blood and Endocrinology Centre | Alexey Yakovlev | RUSSIAN FEDERATION | Saint-Petersburg | Saint-Petersburg |
| City Clinical Hospital #15 | Ivan Gordeev | RUSSIAN FEDERATION | Moscow | Moscow |
| Saint-Petersburg Clinical Hospital #122 | Alexander Gorelov | RUSSIAN FEDERATION | Saint-Petersburg | Saint-Petersburg |
| Saint-Petersburg State Institution of Healthcare | Mikhail Boyarkin | RUSSIAN FEDERATION | Saint-Petersburg | Saint-Petersburg |
| University Children's Hospital | Elena Baranova | RUSSIAN FEDERATION | Saint-Petersburg | Saint-Petersburg |
| Complejo Hospitalario Arquitecto Marcide - Profesor Novoa Santos | Diego Bellido Guerrero | SPAIN | Ferrol | Ferrol |
| COMPLEJO HOSPITALARIO XERAL-CALDE | José Ramón Gonzalez Juanatey | SPAIN | LUGO | LUGO |
| Corporacio Sanitaria Parc Tauli; Servicio de Cardiologia | Josep Guindo Soldevila | SPAIN | SABADELL | SABADELL |
| Fundacion Hospital de Alcorcon | Javier Botas Rodríguez | SPAIN | Alcorcon | Alcorcon |
| Hosp. Clinico San Carlos | Carlos Macaya Miguel | SPAIN | MADRID | MADRID |
| Hospital Clinico Universitario de Santiago | Jose Maria Garcia AcuNa | SPAIN | SANTIAGO DE COMPOSTELA | SANTIAGO DE COMPOSTELA |
| Hospital de Basurto; Servicio de Cardiologia | Nekane Murga Eizagaechevarria | SPAIN | Bilbao | Bilbao |
| Hospital de la Santa Creu; i Sant Pau | Xavier Garcia-Moll Marimon | SPAIN | Barcelona | Barcelona |
| Hospital del Mar Barcelona | Jordi Bruguera Cortada | SPAIN | Barcelona | Barcelona |
| Hospital de Torrevieja | Julio Cesar Blazquez Encinas | SPAIN | Torrevieja | Torrevieja |
| Hospital General De Jerez | Carlos Perez MuNoz | SPAIN | jerez de la frontera | jerez de la frontera |
| HOSPITAL GENERAL UNIV. DE ALICANTE | Alejandro Jordan Torrent | SPAIN | ALICANTE | ALICANTE |
| Hospital General Universitario de Guadalajara | Javier Balaguer Recena | SPAIN | GUADALAJARA | GUADALAJARA |
| Hospital General Universitario De Valencia; Servicio Cardiologia | Francisco Ridocci Soriano | SPAIN | Valencia | Valencia |
| Hospital General Universitario Gregorio MaraNon ; Servicio de Medicina Interna | Francisco Fernandez Aviles | SPAIN | MADRID | MADRID |
| Hospital General Universitario J.M Morales Meseguer | José Antonio Ruiz Ros | SPAIN | Murcia | Murcia |
| Hospital Infanta Sofía | Ignacio Plaza Perez | SPAIN | San Sebastian de los Reyes | San Sebastian de los Reyes |
| Hospital Univ. Central de Asturias | Pablo Avanzas Fernández | SPAIN | Oviedo | Oviedo |
| Hospital Universitari de Bellvitge; Unidad de Riesgo Cardiovascular | Xavier Pinto Sala | SPAIN | HOSPITALET DE LLOBREGAT | HOSPITALET DE LLOBREGAT |
| Hospital Universitari de Sant Joan de Reus; Secció de Cardiologia | Josep Alegre Marti | SPAIN | Reus | Reus |
| Hospital Universitari de Tarragona Joan XXIII | Esther Sanz Girgas | SPAIN | Tarragona | Tarragona |
| Hospital Universitario Virgen de la Victoria; Servicio de Cardiologia | Manuel Jimenez Navarro | SPAIN | Malaga | Malaga |
| Hospital Universitario Virgen Macarena | Miguel Gonzalez-Valdayo Lopez | SPAIN | SEVILLA | SEVILLA |
| Hospital Universitari Vall d'Hebron | Enrique Galve Basilio | SPAIN | Barcelona | Barcelona |
| Hospital Virgen del Mar; Unidad Coronaria | Jose Luis Blanco Coronado | SPAIN | Almeria | Almeria |
| Centralsjukhuset i Karlstad - Central Hospital Karlstad; Department of Cardiology | Riitta Luostarinen | SWEDEN | KARLSTAD | KARLSTAD |
| Danderyd Hospital; Cardiology Department | Pia Lundman | SWEDEN | Danderyd Stockholm | Danderyd Stockholm |
| Hallands sjukhus | Mats Lindgren | SWEDEN | Halmstad | Halmstad |
| Kalmar LAnssjukhus ; Cardiology Department | Mete Axelkvist | SWEDEN | Kalmar | Kalmar |
| Kardiologkliniken | Marianne Soderstrom | SWEDEN | Skovde | Skovde |
| Karolinska University Hospital; Karolinska Institute Cardiology Unit | Linda Mellbin | SWEDEN | Stockholm | Stockholm |
| Ostersund Hospital/Ostersunds sjukhus; Omrade medicin Hjarteenheten | Thomas Mooe | SWEDEN | Ostersund | Ostersund |
| Sahlgrenska Universitetssjukhuset | Per Johanson | SWEDEN | Goteborg | Goteborg |
| SkellefteA Lasarett ; Department of Medicine Research Unit | Kurt Boman | SWEDEN | SkellefteA | SkellefteA |
| SOdersjukhuset | Gunnar Boberg | SWEDEN | Stockholm | Stockholm |
| University Hospital MAS; Cardiology Department | Patrik Tyden | SWEDEN | MalmO | MalmO |
| Buddhachinaraj Phitsanuloke Hospital | Tomon Thongsri | THAILAND | Amphur Muang | Amphur Muang |
| Chiangrai Prachanukros Hospital | Wongtheptian Wattana | THAILAND | Amphur Muang | Amphur Muang |
| Chiangrai Prachanukros Hospital | Wongtheptian Wattana | THAILAND | Amphur Muang | Amphur Muang |
| Chonburi Hospital | Pornchai Ngamjanyaporn | THAILAND | Chonburi | Chonburi |
| Khonkaen Hospital | Prawit Taweesangsuksakul | THAILAND | Khonkaen | Khonkaen |
| KING CHULALONGKORN MEMORIAL HOSPITAL; DIVISION OF CARDIOLOGY, DEPARTMENT OF MEDICINE | SUPHOTSRIMAHACHOTA | THAILAND | BANGKOK | BANGKOK |
| Maharaj Nakorn Chiang Mai Hospital; Department of Medicine | Srun Kuanprasert | THAILAND | ChiangMai | ChiangMai |
| Nakornping Hospital | Khanchai Siriwattana | THAILAND | Amphur Mae-Rim | Amphur Mae-Rim |
| Naresaun University hospital | Thanakorn Laksomya | THAILAND | Phitsanulok | Phitsanulok |
| PHRAMONGKUTKLAO HOSPITAL; CARDIOLOGY UNIT | NAKARIN SANSANAYUDH | THAILAND | BANGKOK | BANGKOK |
| Ramathibodi Hospital; Cardiology Unit | Piyamitr Sritara | THAILAND | Bangkok | Bangkok |
| Saraburi Hospital | Pitha Promlikitchai | THAILAND | Saraburi | Saraburi |
| Siriraj Hospital, Mahidol University; Department of Medicine, Faculty of Medicine | Damras Tresukosol | THAILAND | Bangkok | Bangkok |
| SRINAGARIND HOSPITAL, KHON KAEN UNI ; DEPT OF MEDICINE | Chaiyasith Wongwipaporn | THAILAND | KHON KAEN | KHON KAEN |
| Thammasat Chalermprakiat Hospital at Thammasat University; Thammasat Heart Center | Pisit Hutayanon | THAILAND | Klong Luang | Klong Luang |
| Vajira Hospital and Medical College; Cardiology Department | Paiboon Chotnoparatpat | THAILAND | Bangkok | Bangkok |
| Addenbrooke's Hospital | David Dutka | UNITED KINGDOM | Cambridge | Cambridge |
| Altnagelvin Area Hospital | John Purvis | UNITED KINGDOM | LONDONDERRY | LONDONDERRY |
| Antrim Area Hospital | Tom Trouton | UNITED KINGDOM | Antrim | Antrim |
| Ayr Hospital; Diabetes Centre | Andrew Collier | UNITED KINGDOM | AYR | AYR |
| Ballygomartin Group Practice | Simon Hutchinson | UNITED KINGDOM | Belfast | Belfast |
| Barts and the London NHS Trust; LRN Diabetes | Ceri Davies | UNITED KINGDOM | London | London |
| Basildon University Hospital; Dept of Cardiology | Rajesh Aggarwal | UNITED KINGDOM | Basildon | Basildon |
| Brighton & Sussex University Hospitals; Cardiac Research Unit | David Hildick-Smith | UNITED KINGDOM | Brighton | Brighton |
| Diabetes Clinical Research Centre, Peninsula Medical School | Beverley Millward | UNITED KINGDOM | Plymouth | Plymouth |
| Ealing Hospital; Cardiology Department | Jaspal Kooner | UNITED KINGDOM | Southall | Southall |
| Highland Clinical Research Facility; Centre for Health Science | Sandra MacRury | UNITED KINGDOM | Inverness | Inverness |
| International Centre for Circulatory Health; Imperial College Healthcare Trust | Iqbal Malik | UNITED KINGDOM | Paddington | Paddington |
| Maelor Hospital, Betsi Cadwaladr University Health Board | John Harvey | UNITED KINGDOM | Wrexham | Wrexham |
| Northampton General Hospital; Department of Cardiology Research | Dominic Cox | UNITED KINGDOM | NORTHAMPTON | NORTHAMPTON |
| Northwick Park Hospital; Cardiology | Roxy Senior | UNITED KINGDOM | Harrow | Harrow |
| Poole Hospital; Cardiorespiratory Dept | Diane Bruce | UNITED KINGDOM | POOLE | POOLE |
| Queens Hospital; Romford Cardio Research | Honer Kadr | UNITED KINGDOM | Romford | Romford |
| Royal Derby Hospital; Medical School | Frances Game | UNITED KINGDOM | Derby | Derby |
| Royal United Hospital Bath; Diabetes and Lipid Research, Wolfson Centre | John Reckless | UNITED KINGDOM | Bath | Bath |
| Sandwell General Hospital; Sandwell Medical Research Unit | Douglas Robertson | UNITED KINGDOM | WEST BROMWICH | WEST BROMWICH |
| ST MARY'S HOSPITAL; VECTASEARCH CLINIC | DALLAS PRICE | UNITED KINGDOM | NEWPORT | NEWPORT |
| University Hospital of North Staffordshire City General Hospital; Dept of Cardiology | Robert Butler | UNITED KINGDOM | Stoker on Trent | Stoker on Trent |
| University of Leeds | Ramzi Ajjan | UNITED KINGDOM | Leeds | Leeds |
| Western Infirmary | Gordon McInnes | UNITED KINGDOM | Glasgow | Glasgow |
| West Middlesex University Hospital; RACPC Outpatients 2 | Raffi Kaprielian | UNITED KINGDOM | Isleworth | Isleworth |
| Abbott Northwestern Hospital, Allina Medical Systems | Thomas Knickelbine | UNITED KINGDOM | Minneapolis | Minneapolis |
| Academic Medical Research Institute, Inc | MOHAMED EL-SHAHAWY | UNITED KINGDOM | Glendale | Glendale |
| Advanced Heart Care LLC | Sharan Mahal | UNITED KINGDOM | Bridgewater | Bridgewater |
| Alexandria Cardiology Clinic | Naseem Jaffrani | UNITED KINGDOM | Alexandria | Alexandria |
| Alle - Kiski Medical Center | Venkatraman Srinivasan | UNITED STATES | Natrona Heights | Natrona Heights |
| Alpena General Hospital | Abraham Salacata | UNITED STATES | Alpena | Alpena |
| Amarillo Heart Clinical Research Institute, Inc | Ernesto Rivera | UNITED STATES | Amarillo | Amarillo |
| American Clinical Trial | Paul Staab | UNITED STATES | Marrero | Marrero |
| Anne Arundel Medical Center | James Welker | UNITED STATES | Annapolis | Annapolis |
| Apex Medical Research | Akber Mohammed | UNITED STATES | Springfield | Springfield |
| Atlantic Cardiology Associates PA | Anthony Frey | UNITED STATES | Salisbury | Salisbury |
| AUDIE L. MURPHY MEMORIAL VETERANS HOSPITAL; SOUTH TEXAS VETERANS HEALTH CARE SYSTEM | ROBERT CHILTON | UNITED STATES | San Antonio | San Antonio |
| Aurora Burlington Clinic | Stephen Welka | UNITED STATES | Burlington | Burlington |
| Aurora Denver Cardiology Associates PC | Nampalli Vijay | UNITED STATES | Denver | Denver |
| AURORA HEALTH CARE CLINICAL RESEARCH | Yoseph Shalev | UNITED STATES | Milwaukee | Milwaukee |
| Bay Regional Medical Center | Daniel Lee | UNITED STATES | Bay City | Bay City |
| Ben Taub General Hospital; Cardiology | Rajiv Goswami | UNITED STATES | Houston | Houston |
| Beth Israel Deaconess Medical Center | David Halloran | UNITED STATES | Boston | Boston |
| Borgess Medical Center/Borgess Research Institute | Vishal Gupta | UNITED STATES | Kalamazoo | Kalamazoo |
| Broward General Medical Center | David Perloff | UNITED STATES | Ft. Lauderdale | Ft. Lauderdale |
| Buffalo Heart Group | Joseph Gelormini | UNITED STATES | Buffalo | Buffalo |
| Cape Cod Research Institute | Richard Zelman | UNITED STATES | Hyannis | Hyannis |
| Cardiac Care and Vascular Medicine | Michele Nanna | UNITED STATES | Bronx | Bronx |
| CardioCare of South Florida PA | Eric Spivack | UNITED STATES | Aventura | Aventura |
| Cardiology Associates of Green Bay, Ltd. | James Rider | UNITED STATES | Green Bay | Green Bay |
| Cardiology Consultants of Orange County Medical Grp | Harinder Gogia | UNITED STATES | Anaheim | Anaheim |
| Cardiology, PC | James Longo | UNITED STATES | Syracuse | Syracuse |
| Cardiology, PC | Alain Bouchard | UNITED STATES | Syracuse | Syracuse |
| Cardiovascular Associates of Fairfield | Edward Portnay | UNITED STATES | Stamford | Stamford |
| Cardiovascular Associates of North Alabama, PC | Andrew Miller | UNITED STATES | Birmingham | Birmingham |
| Cardiovascular Consultants Inc | John Prodafikas | UNITED STATES | Canton | Canton |
| Cardiovascular Institute of the South | Vinod Nair | UNITED STATES | Houma | Houma |
| Cardiovascular Research Center of South Florida | Jonathan Fialkow | UNITED STATES | Miami | Miami |
| Cardiovascular Specialists. LLC | William Herzog | UNITED STATES | Columbia | Columbia |
| CARE Clinical Research | Henri Marais | UNITED STATES | Banning | Banning |
| Carl and Edyth Lindner Center at Christ Hospital | DEAN KEREIAKES | UNITED STATES | CINCINNATI | CINCINNATI |
| CENTRAL JERSEY HEALTH CENTER | MANDEEP OBEROI | UNITED STATES | Elizabeth | Elizabeth |
| Central Michigan Community Hospital | Scott Martin | UNITED STATES | Saginaw | Saginaw |
| Central MN Heart Center at St. Cloud Hospital | Timothy Schuchard | UNITED STATES | St. Cloud | St. Cloud |
| Chambersburg Hospital | Aylmer Tang | UNITED STATES | Chambersburg | Chambersburg |
| Chest and Critical Care Consultants | Nguyen Dang | UNITED STATES | Anaheim | Anaheim |
| Chrishard Medical Group | Cranford Scott | UNITED STATES | Inglewood | Inglewood |
| Clinical Trials of St. Jude | John Gilbert | UNITED STATES | FULLERTON | FULLERTON |
| Coastal Multi-Specialty Research | Anil Shah | UNITED STATES | Santa Ana | Santa Ana |
| Columbia University Medical Center | Giora Weisz | UNITED STATES | New York | New York |
| Connecticut Clinical Research LLC | Edward Kosinski | UNITED STATES | Bridgeport | Bridgeport |
| DALLAS VA MEDICAL CENTER | Padmashri Rastogi | UNITED STATES | Dallas | Dallas |
| Diabetes Associates Med Group | Ivy-Joan Madu | UNITED STATES | Orange | Orange |
| DM Clinical Research | Aditya Samal | UNITED STATES | Tomball | Tomball |
| Dorothy H. Banish, MD, APMC | George Isa | UNITED STATES | Convington | Convington |
| Eastern Cardiology, P.A. | Eric Carlson | UNITED STATES | Greenville | Greenville |
| East Texas Cardiology PA | Anwar Ahmad | UNITED STATES | Houston | Houston |
| Edgewater Medical Research, Inc. | Eric Lo | UNITED STATES | Edgewater | Edgewater |
| Endocrine Research Associates | Robert Evans | UNITED STATES | Jackson | Jackson |
| Endocrinology Associates, Inc | Elena Christofides | UNITED STATES | Columbus | Columbus |
| Franciscan Skemp Healthcare System | Tahir Tak | UNITED STATES | LaCrosse | LaCrosse |
| Future Care Solution LLC | Londono Juan | UNITED STATES | Hialeah | Hialeah |
| Geisinger Clinic; Breast Clinic Department of General Surgery | Steven Steinhubl | UNITED STATES | Danville | Danville |
| Genesis Health System | Eric Dippel | UNITED STATES | Davenport | Davenport |
| G & G Research | Howard Tee | UNITED STATES | Vero Beach | Vero Beach |
| Great Falls Clinic; Clinical Research Department | William Rowe | UNITED STATES | Great Falls | Great Falls |
| HARTFORD HOSPITAL | Donna Polk | UNITED STATES | Hartford | Hartford |
| HCMC Cardiology Research | Woubeshet Ayenew | UNITED STATES | Minneapolis | Minneapolis |
| HealthEast St Joseph's Hosp | Les Forgosh | UNITED STATES | Saint Paul | Saint Paul |
| Heart and Vascular Center of New Brunswick, LLC | Dinesh Singal | UNITED STATES | Somerset | Somerset |
| Heart and Vascular Institute of Florida | Robert Sanchez | UNITED STATES | St. Petersburg | St. Petersburg |
| HIGHTOP MEDICAL RESEARCH CENTER | JAMES FIDELHOLTZ | UNITED STATES | CINCINNATI | CINCINNATI |
| Holy Cross Medical Group | Ricky Schneider | UNITED STATES | Coral Springs | Coral Springs |
| IDS LA BioMed at Harbor-UCLA | Matthew Budoff | UNITED STATES | Torrance | Torrance |
| Internal Medicine Associates of Morris County | Mark Quadrel | UNITED STATES | Mine Hill | Mine Hill |
| Interventional Cardiac Consultants | Carlos Bayron | UNITED STATES | Trinity | Trinity |
| Jacksonville Heart Center | Thomas Hilton | UNITED STATES | Jacksonville Beach | Jacksonville Beach |
| Jefferson Heart Institute | John Doherty | UNITED STATES | Philadelphia | Philadelphia |
| Kandra Fierer Kuskin Associates, Ltd. | Robert Fierer | UNITED STATES | Harrisburg | Harrisburg |
| Kore Cardiology Research Institute | Elie Korban | UNITED STATES | Lexington | Lexington |
| Legacy Heart Center | Marcus McKenzie | UNITED STATES | Plano | Plano |
| Louisiana Heart Center | Jay Silverstein | UNITED STATES | Hammond | Hammond |
| Louisiana Heart Center | Keith Hickey | UNITED STATES | LaPlace | LaPlace |
| LOUISIANA HEART CENTER | BRUCE ITELD | UNITED STATES | SLIDELL | SLIDELL |
| LSU Health Sciences Center | Klagi Modi | UNITED STATES | SHREVEPORT | SHREVEPORT |
| Mayo Clinic Rochester | Patricia Best | UNITED STATES | Rochester | Rochester |
| McFarland Clinic | Imran Dotani | UNITED STATES | Ames | Ames |
| Mclaren Regional Medical Center; Research Institute | Jeffrey Harris | UNITED STATES | Flint | Flint |
| Medical Tech., Inc. | Salah El Hafi | UNITED STATES | Houston | Houston |
| MediQuest Research Group Inc. at Munroe Regional Medical Center | Robert Feldman | UNITED STATES | Ocala | Ocala |
| Mehrdad Ariani, M.D., Inc. | Mehrdad Ariani | UNITED STATES | Northridge | Northridge |
| Memorial Hermann | Francisco Maislos | UNITED STATES | Houston | Houston |
| Memorial Hospital of Rhode Island | Charles Eaton | UNITED STATES | Pawtucket | Pawtucket |
| Mercy Clinic East Communities d/b/a/ Mercy Health Research | John Mohart | UNITED STATES | Washington | Washington |
| Mercy St. Vincent Medical Center | Ameer Kabour | UNITED STATES | Toledo | Toledo |
| Miami International Cardiology Consultants | Ali Bazzi | UNITED STATES | Aventura | Aventura |
| Mid-Michigan Heart and Vascular Center, P.C. | John McClure | UNITED STATES | Saginaw | Saginaw |
| Midwest Cardiovascular Research & Education Foundation; Cardiology | Charles Mathis | UNITED STATES | Elkhart | Elkhart |
| Miriam Hospital | Paul Gordon | UNITED STATES | Providence | Providence |
| Misal Khan M.D. FRCS(Ed)P.A. | Misal Khan | UNITED STATES | Panama City | Panama City |
| Mountainview Clinical Research | PHILIP SNELL | UNITED STATES | Greer | Greer |
| Mount Sinai Medical Center | Robert Rosenson | UNITED STATES | New York | New York |
| Naidu Clinic | Jayaram Naidu | UNITED STATES | Odessa | Odessa |
| Nanticoke Cardiology, P.A. | Donald Laurion | UNITED STATES | Seaford | Seaford |
| New Mexico Heart Institute | Mark Bieniarz | UNITED STATES | Albuquerque | Albuquerque |
| New York Methodist Hospital | Sorin Brener | UNITED STATES | Brooklyn | Brooklyn |
| Nisus Research/Northern Michigan Hospital | Harry Colfer | UNITED STATES | PETOSKEY | PETOSKEY |
| Northeast Cardiology Associates | Peter Ver Lee | UNITED STATES | Bangor | Bangor |
| North West Heart Center | Mustafa Mandviwala | UNITED STATES | Tomball | Tomball |
| OCHSNER CLINIC FOUNDATION | Patrick Breaux | UNITED STATES | NEW ORLEANS | NEW ORLEANS |
| Ohio State University Med Ctr; MS Center | Raymond Magorien | UNITED STATES | COLUMBUS | COLUMBUS |
| Olive View/Ucla Medical Center | Traina Mahmoud | UNITED STATES | Sylmar | Sylmar |
| OREGON HEALTH & SCIENCE UNI | Stephen Heitner | UNITED STATES | PORTLAND | PORTLAND |
| Orlando Health Inc. | Robert Dalton | UNITED STATES | Orlando | Orlando |
| Overlea Personal Physicians | Brian Kahn | UNITED STATES | Baltimore | Baltimore |
| Overton Brooks VA Medical Center | Neeraj Tandon | UNITED STATES | Shreveport | Shreveport |
| Pennsylvania Cardiology Assocs | Robert Norris | UNITED STATES | Philadelphia | Philadelphia |
| Pepin Heart & Vascular Institute Univ. Community Hospital | Charles Lambert | UNITED STATES | Tampa | Tampa |
| Pharma Tex Research | Sammy Cox | UNITED STATES | Amarillo | Amarillo |
| Pikes Peak Cardiology LLP | Ronald Blonder | UNITED STATES | Colorado Springs | Colorado Springs |
| Pottstown Medical Specialists | Joseph Krantzler | UNITED STATES | Pottstown | Pottstown |
| PriMed Clinical Research | William Randall | UNITED STATES | Kettering | Kettering |
| Quality of Life Medical & Research Center | John McGettigan | UNITED STATES | Tucson | Tucson |
| Research Concepts, LTD | Stuart Jacobson | UNITED STATES | Bellaire | Bellaire |
| Research Integrity | Kishor Vora | UNITED STATES | Owensboro | Owensboro |
| Rhode Island Hospital; Hallett Center | Geetha Gopalakrishnan | UNITED STATES | Providence | Providence |
| Roanoke Heart Institute, PLC | John Jr.Schmedtje | UNITED STATES | Roanoke | Roanoke |
| Sarasota Memorial Hospital; Clinical Research Center | Chippy Nalluri | UNITED STATES | Sarasota | Sarasota |
| Seton Heart Institute | Mark Pirwitz | UNITED STATES | Austin | Austin |
| SOFHA Clinical Research | Brian Way | UNITED STATES | Johnson City | Johnson City |
| Southern Clinical Research | Charles Thompson | UNITED STATES | Zachary | Zachary |
| South Texas Cardiovascular | Michael Melucci | UNITED STATES | Kerrville | Kerrville |
| South Texas Cardiovascular Consultants | Abram Rabinowitz | UNITED STATES | San Antonio | San Antonio |
| Southwest Cardiovascular Consultants | Richard Fish | UNITED STATES | Houston | Houston |
| Southwest General Health Center | Touraj Taghizadeh | UNITED STATES | Middleburg Heights | Middleburg Heights |
| Suncoast Cardiovascular Research | Vibhuti Singh | UNITED STATES | St. Petersburg | St. Petersburg |
| Sunrise Clinical Research Inc. | Howard Berlin | UNITED STATES | Hollywood | Hollywood |
| Swicft Institute | James Talano | UNITED STATES | Naples | Naples |
| Temple University Hospital | Riyaz Bashir | UNITED STATES | PHILADELPHIA | PHILADELPHIA |
| Tennessee Center for Clinical Trials | Dinesh Kumar Gupta | UNITED STATES | Tullahoma | Tullahoma |
| Texas Cardiac Center | Mohammad Shoukfeh | UNITED STATES | Lubbock | Lubbock |
| Texas Cardiology Associated of Houston | Ira Lieber | UNITED STATES | Kingwood | Kingwood |
| The Cardiac Center of Creighton University | Aryan Mooss | UNITED STATES | Omaha | Omaha |
| The Care Group, LLC | James Hermiller | UNITED STATES | Indianapolis | Indianapolis |
| The Endocrine Group | Robert Busch | UNITED STATES | Albany | Albany |
| The Heart & Vascular Clinic | Gina Chandler | UNITED STATES | Nashville | Nashville |
| The Heart & Vascular Institute of Florida | Alan Camp | UNITED STATES | Clearwater | Clearwater |
| UAB Medical Center | Rogers Williams | UNITED STATES | Birmingham | Birmingham |
| UCSF Mount Zion Medical Ctr | Gordon Fung | UNITED STATES | San Francisco | San Francisco |
| UNI OF TEXAS SOUTHWESTERN MEDICAL CENTER | Darren McGuire | UNITED STATES | Dallas | Dallas |
| Universal Clinical Research Associates | Luis Martinez | UNITED STATES | Doral | Doral |
| University Cardiovascular Services | Mark Studeny | UNITED STATES | Huntington | Huntington |
| University Medical Practice Associates | Jeanine Albu | UNITED STATES | New York | New York |
| University of Arizona Health Science Center;Division of Gynecology | Kwan Lee | UNITED STATES | Tucson | Tucson |
| University of California San Diego Research | Ajit Raisinghani | UNITED STATES | San Diego | San Diego |
| University of Maryland Medical System; Division Of Cardiology | MICHAEL MILLER | UNITED STATES | BALTIMORE | BALTIMORE |
| University of Medicine and Dentistry of New Jersey-NJMS | Edo Kaluski | UNITED STATES | Newark | Newark |
| University of Miami School of Medicine | RONALD GOLDBERG | UNITED STATES | Miami | Miami |
| University of Michigan Medical Center | Rodica Pop Busui | UNITED STATES | Ann Arbor | Ann Arbor |
| University of New Mexico | Allen Adolphe | UNITED STATES | Albuquerque | Albuquerque |
| University of South Alabama ; Department of Cardiology | Bassam Omar | UNITED STATES | Mobile | Mobile |
| University of Southern California; Division of Cardiovascular Medicine | Leonardo Clavijo | UNITED STATES | Los Angeles | Los Angeles |
| University of Texas Health Science Center at San Antonio | Alexander Shepherd | UNITED STATES | San Antonio | San Antonio |
| Utah Cardiology | Daniel Humiston | UNITED STATES | Layton | Layton |
| Valley Research | Paul Norwood | UNITED STATES | Fresno | Fresno |
| VA Long Beach Healthcare System | ELLIS LEVIN | UNITED STATES | Long Beach | Long Beach |
| VA MEDICAL CENTER | Yellapragada Chandrashekar | UNITED STATES | MINNEAPOLIS | MINNEAPOLIS |
| VA Medical Center Dayton OH | Mohammad Saklayen | UNITED STATES | Dayton | Dayton |
| VA Medical Center-Denver; Cardiology Department | Gregory Schwartz | UNITED STATES | Denver | Denver |
| Vernon Medical Center | Jang Singh | UNITED STATES | Worcester | Worcester |
| Victoria Heart & Vascular Center | Harish Chandna | UNITED STATES | Victoria | Victoria |
| Virginia Research Institute | Bosh Zakhary | UNITED STATES | Danville | Danville |
| Wake Forest University Center for Genomic | David Herrington | UNITED STATES | Winston-Salem | Winston-Salem |
| Weill Cornell Medical College | Bassem Masri | UNITED STATES | New York | New York |
| Westlake Medical Research Inc. | Irving Loh | UNITED STATES | Thousand Oaks | Thousand Oaks |
| Westroads Medical Group | WILLIAM PALMER | UNITED STATES | Omaha | Omaha |
| William Beaumont Hospital | Peter McCullough | UNITED STATES | Royal Oak | Royal Oak |
| Zablocki VAMC Milwaukee | Hossein Almassi | UNITED STATES | Milwaukee | Milwaukee |
| ZASA Clinical Research | Debra Weinstein | UNITED STATES | BOYNTON BEACH | BOYNTON BEACH |
伦理委员会信息
| 名称 | 审查结论 | 审查日期 |
|---|---|---|
| 上海市第六人民医院伦理委员会 | 同意 | 2012-07-25 |
| 四川大学华西医院临床试验与生物医学伦理专委会 | 同意 | 2012-08-01 |
| 西安交通大学医学院第一附属医院医学伦理委员会 | 同意 | 2012-08-03 |
| 上海交通大学医学院附属第九人民医院伦理委员会 | 同意 | 2012-08-23 |
| 湖南省人民医院医学伦理委员会 | 同意 | 2012-08-31 |
| 上海市第十人民医院伦理委员会 | 同意 | 2012-10-25 |
| 上海市徐汇区中心医院伦理委员会 | 同意 | 2013-04-18 |
| 浙江医院医学伦理委员会 | 同意 | 2013-04-24 |
| 青岛市市立医院伦理委员会 | 同意 | 2013-04-24 |
| 中山大学附属第一医院临床药品、设备和医疗新技术伦理委员会 | 同意 | 2013-04-28 |
| 浙江大学医学院附属第一医院医学伦理委员会 | 同意 | 2013-04-29 |
| 北京军区总医院药物临床试验机构伦理委员会 | 同意 | 2013-05-02 |
| 中国人民解放军沈阳军区总医院医学伦理委员会 | 同意 | 2013-05-06 |
| 东南大学附属中大医院临床研究伦理委员会 | 同意 | 2013-05-08 |
| 中南大学湘雅二医院伦理委员会 | 同意 | 2013-05-08 |
| 中国人民解放军总医院医学伦理委员会 | 同意 | 2013-05-09 |
| 武汉大学中南医院医学伦理委员会 | 同意 | 2013-05-15 |
| 北京协和医院药物临床试验伦理委员会 | 同意 | 2013-05-15 |
| 首都医科大学附属北京友谊医院药物临床试验伦理委员会 | 同意 | 2013-05-16 |
| 中国人民解放军第二五四医院伦理委员会 | 同意 | 2013-05-16 |
| 中南大学湘雅三医院医学伦理委员会 | 修改后同意 | 2013-05-17 |
| 山东省齐鲁医院药物临床试验伦理委员会 | 同意 | 2013-05-22 |
| 辽宁省人民医院伦理委员会 | 同意 | 2013-05-24 |
| 包头市中心医院药物临床试验伦理委员会201894 | 同意 | 2013-05-24 |
| 第二炮兵总医院伦理委员会 | 同意 | 2013-05-29 |
| 浙江大学医学院附属邵逸夫医院伦理委员会 | 同意 | 2013-05-29 |
| 复旦大学附属华山医院伦理审查委员会 | 同意 | 2013-05-30 |
| 北京安贞医院药物临床研究伦理委员会 | 同意 | 2013-06-03 |
| 中国医科大学附属盛京医院伦理委员会 | 同意 | 2013-06-07 |
| 上海交通大学医学院附属仁济医院伦理委员会 | 同意 | 2013-06-13 |
| 上海市同济医院伦理委员会 | 同意 | 2013-06-14 |
| 中日友好医院药物/器械临床试验伦理委员会 | 同意 | 2013-06-20 |
| 广西医科大学第一附属医院医学伦理委员会 | 同意 | 2013-06-20 |
| 白求恩国际和平医院临床研究医学伦理委员会 | 同意 | 2013-06-20 |
| 首都医科大学附属北京朝阳医院医学伦理委员会 | 同意 | 2013-06-25 |
| 大庆油田总医院伦理委员会 | 同意 | 2013-07-12 |
| 大连医科大学附属第一医院医学伦理委员会 | 同意 | 2013-07-16 |
| 上海市胸科医院伦理委员会 | 同意 | 2013-07-17 |
| 广东省人民医院医学伦理委员会 | 同意 | 2013-07-17 |
| 中国人民解放军第306医院药物临床试验医学伦理委员会 | 同意 | 2013-07-18 |
| 首都医科大学附属北京世纪医院医学伦理委员会 | 同意 | 2013-08-02 |
试验状态信息
试验状态
主动暂停
目标入组人数
国内: 300 人；
国际: 7000 人；
已入组例数
国内: 登记人暂未填写该信息；
国际: 登记人暂未填写该信息；
实际入组总例数
国内: 630 人 ；
国际: 7226 人；
第一例受试者签署知情同意书日期
国内：登记人暂未填写该信息；
国际：登记人暂未填写该信息；
第一例受试者入组日期
国内：2010-08-19；
国际：2010-01-05；
试验终止日期
国内：登记人暂未填写该信息；
国际：登记人暂未填写该信息；
临床试验结果摘要
| 版本号 | 版本日期 |
|---|
